Dr. Lea Tenenholz Grinberg is a neuropathologist specializing in brain aging and associated disorders, most notably, Alzheimer's and neurological basis of sleep disturbances in neurodegenerative diseases. Currently, she is a Full Professor and a John Douglas French Alzheimer's Foundation Endowed Professor at the UCSF Memory and Aging Center, part of the Executive Board of the Global Brain Health Institute and a member of the Medical Scientific Advisory Group for the Alzheimer Association. She is also a Professor of Pathology at the University of Sao Paulo.
The Kampmann lab develops and applies innovative technologies to understand cellular and molecular mechanisms of aging-associated neurodegenerative diseases, and to discover new therapeutic strategies. A major focus of our research are Alzheimer's disease and related dementias.
Our lab investigates how small molecules perturb protein target networks to biological and therapeutic effect. In a forward polypharmacology campaign, we are using machine learning and computational methods such as the Similarity Ensemble Approach (SEA) to infer new combinations of targets underlying compound-induced phenotypes in cells and broader model systems. Thinking of each target as a musical note, we predict and test entire chords at a time via chemical-genetic epistasis experiments in models of complex diseases such as neurodegeneration.
Joel Kramer is a neuropsychologist, a specialist in the relationship between the central nervous system and behaviors. He directs the neuropsychology program at the UCSF Memory and Aging Center, where he helps to diagnose and care for patients with a wide range of memory disorders.
In his research, Kramer studies the effects of neurodegenerative disease on intellectual abilities and behavior, behavioral markers of Alzheimer's disease before clear symptoms appear, and cognitive changes associated with typical aging.
Dr. Krystal is the Ray and Dagmar Dolby Distinguished Professor in the Departments of Psychiatry and Neurology, Vice-Chair for Research in the Department of Psychiatry, Director of the Dolby Family Center for Mood Disorders, Director of the UCSF Interventional Psychiatry Program and Co-Director of the TMS & Neuromodulation Clinic. He is Board Certified in Clinical Neurophysiology by the American Board of Clinical Neurophysiology and the American Board of Psychiatry and Neurology and Board Certified in Psychiatry by the American Board of Psychiatry and Neurology.
Kevin was born and raised in San Francisco, California. He attended UC Davis and graduated with a bachelor's of science degree in neurobiology, physiology and behavior and a bachelors’ of arts degree in psychology. Before joining the Memory and Aging Center, Kevin volunteered at On Lok Lifeways and interacted with Chinese elders in Chinatown. He is currently a research coordinator for the UCSF Alzheimer’s Disease Research Center. He coordinates visits for the Cantonese- and English-speaking Chinese participants.
Dr. Ljubenkov received his medical degree from Temple University School of Medicine in Philadelphia. During his training he took part in the Medical Student Training in Aging Research (MSTAR) program at University of California, Los Angeles, where he investigated midbrain and basal ganglia pathology in patients with Alzheimer’s disease. He went on to complete his internship in internal medicine at the University of California, Irvine, and his residency in neurology at University of California, San Diego.
Dr. Neylan is a Professor, In Residence in the Departments of Psychiatry and Neurology at the University of California, San Francisco. He is the Director of the Posttraumatic Stress Disorders (PTSD) Clinic and the Stress and Health Research Program at the San Francisco Veterans Affairs Medical Center. His research has focused on the role of sleep in emotion regulation, cognitive function, and metabolic health, in patients with PTSD and in aging populations with neurodegenerative disorders.
Vy is a program manager at the Parkinson’s Spectrum Disorders Center, and her work focuses on research projects involving the diagnosis, care and prevention of Parkinson’s spectrum disorders.
