Fanny Elahi, MD, PhD

Assistant Professor
Memory and Aging Center
+1 415 476-6880

Fanny Elahi is a board-certified neurologist with specific expertise in the evaluation and management of patients with cognitive and behavioral disorders due to degenerative brain diseases such as Alzheimer's disease and related disorders. She completed her bachelor's degree at Columbia University, her MD from Icahn School of Medicine, at Mount Sinai, and her DPhil from Oxford University. She pursued her residency in neurology at the University of California, Los Angeles and joined the University of California, San Francisco Memory and Aging Center in 2015 where she trained in neurodegenerative disorders prior to joining the faculty in the department of Neurology. Her research is focused on the identification of early biomarkers of degenerative brain disease with a particular interest in characterization of contributions of immune dysregulation and vascular disease to brain dysfunction, mood and cognitive changes, and ultimately progressive brain degeneration. Her work has been supported by the American Academy of Neurology in partnership with the Allergan foundation, the Alzheimer's Disease Research Center at the UCSF Memory and Aging Center, the National Institute of Neurological Disorders and Stroke, as well as philanthropic donations.

Publications: 

White Matter Hyperintensities: Complex Predictor of Complex Outcomes.

Journal of the American Heart Association

Karvelas N, Elahi FM

Clinical trials in vascular cognitive impairment following SPRINT-MIND: An international perspective.

Cell reports. Medicine

Elahi FM, Alladi S, Black SE, Claassen JAHR, DeCarli C, Hughes TM, Moonen J, Pajewski NM, Price BR, Satizabal C, Shaaban CE, Silva NCBS, Snyder HM, Sveikata L, Williamson JD, Wolters FJ, Hainsworth AH

Novel grading system for CADASIL severity: A multicenter cross-sectional study.

Cerebral Circulation - Cognition and Behavior

Anisetti B, Greco E, Stojadinovic E, Goldstein ED, Sakusic A, Badi MK, Liu MD, Lin MP, Chiang CC, Elahi FM, Worrall BB, Petrosian D, Ross O, Meschia JF

Placental growth factor as a sensitive biomarker for vascular cognitive impairment.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Hinman JD, Elahi F, Chong D, Radabaugh H, Ferguson A, Maillard P, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Wilcock D, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, DeCarli C, Kramer J

Immune cell counts in cerebrospinal fluid predict cognitive function in aging and neurodegenerative disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Snyder A, Grant H, Chou A, Lindbergh CA, Kramer JH, Miller BL, Elahi FM

Blood-brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain.

Alzheimer's & Dementia

Yasmine Tabdili, Krystal Courtney D Belmonte, Nivetha Brathaban, Emma Iorio, Ryan Park, Anna M VandeBunte, Kaitlin B Casaletto, Joel H. Kramer, Katerina Akassoglou, Fanny M Elahi

Sex modifies the association between hippocampal blood flow and episodic memory in cognitively unimpaired individuals.

Alzheimer's & Dementia

Anna Brugulat-Serrat, Yann Cobigo, Corrina S. Fonseca, Torie Tsuei, Lauren Goldberger, Howard J. Rosen, Joel H. Kramer, Fanny M Elahi, Adam M. Staffaroni, Kaitlin B Casaletto

Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.

Cell

Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D

Right temporal lobe and socioemotional semantics: semantic behavioural variant frontotemporal dementia.

Brain : a journal of neurology

Younes K, Borghesani V, Montembeault M, Spina S, Mandelli ML, Welch AE, Weis E, Callahan P, Elahi FM, Hua AY, Perry DC, Karydas A, Geschwind D, Huang E, Grinberg LT, Kramer JH, Boxer AL, Rabinovici GD, Rosen HJ, Seeley WW, Miller ZA, Miller BL, Sturm VE, Rankin KP, Luisa Gorno-Tempini M

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.

Alzheimer's & dementia (Amsterdam, Netherlands)

Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ

Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, Chan JR, Green AJ

Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

CSF and plasma placental growth factor as a biomarker for small-vessel damage in VCID.

Alzheimer's & Dementia

Tiffany L Sudduth, Zachary Winder, Fanny M Elahi, Peter T Nelson, Gregory A Jicha, Donna M Wilcock

Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology.

Alzheimer's & Dementia

Ahmed Abdelhak, Isaac Solomon, Alexandra Saias, Shivany Condor Montes, Christian Cordano, Breton Asken, Corrina Fonseca, Frederike Cosima Oertel, Konstantinos Arfanakis, Adam M. Staffaroni, Michael Geschwind, Fanny M. Elahi, Ari J. Green

Plasma Biomarkers of Angiogenesis Related to Small Vessel Brain Disease in SPRINT.

Innovation in aging

Nicholas Pajewski, Fanny Elahi, Joachim Ix, Ilya Nasrallah, Jason Hinman, Lenore Launer, Jeff Williamson, Donna Wilcock

Plasma Biomarkers of Angiogenesis Related to Small Vessel Brain Disease in SPRINT.

Innovation in aging

Nicholas Pajewski, Fanny Elahi, Joachim Ix, Ilya Nasrallah, Jason Hinman, Lenore Launer, Jeff Williamson, Donna Wilcock

Retinal biomarkers predict future cognitive performance in progranulin-haploinsufficient frontotemporal dementia.

Alzheimer's & Dementia

Frederike Cosima Oertel, Kyan Younes, Yann Cobigo, Azeen Keihani, Corrina Fonseca, Daniel J Bennett, Ahmed Abdelhak, Alexandra Saias, Shivany Condor Montes, Robert Y Chen, Christian Cordano, Ari J Green, Fanny M Elahi

Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Pajewski NM, Elahi FM, Tamura MK, Hinman JD, Nasrallah IM, Ix JH, Miller LM, Launer LJ, Wright CB, Supiano MA, Lerner AJ, Sudduth TL, Killeen AA, Cheung AK, Reboussin DM, Wilcock DM, Williamson JD

Inter-Batch Reliability of Blood-Based Cytokine and Chemokine Measurements in Community-Dwelling Older Adults: A Cross-Sectional Study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Asken BM, Casaletto KB, Elahi FM, Goldberger LA, Fonseca C, You M, Apple AC, Staffaroni AM, Fitch R, Rivera Contreras W, Wang P, Karydas A, Kramer JH, Hillblom Aging Network

Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition.

GeroScience

Whitehead SN, Bruno A, Burns JM, Carmichael ST, Csiszar A, Edwards JD, Elahi FM, Faraco G, Gould DB, Gustafson DR, Hachinski V, Rosenberg G, Sorond FA, Shih AY, Tse KH, Ungvari Z, Wilcock DM, Zuloaga KL, Barone FC

Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.

Journal of the International Neuropsychological Society : JINS

Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB

Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Sexton CE, Anstey KJ, Baldacci F, Barnum CJ, Barron AM, Blennow K, Brodaty H, Burnham S, Elahi FM, Götz J, Jeon YH, Koronyo-Hamaoui M, Landau SM, Lautenschlager NT, Laws SM, Lipnicki DM, Lu H, Masters CL, Moyle W, Nakamura A, Pasinetti GM, Rao N, Rowe C, Sachdev PS, Schofield PR, Sigurdsson EM, Smith K, Srikanth V, Szoeke C, Tansey MG, Whitmer R, Wilcock D, Wong TY, Bain LJ, Carrillo MC

Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.

Alzheimer's & dementia (Amsterdam, Netherlands)

Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH

APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.

Hippocampus

Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH

Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis.

BMJ (Clinical research ed.)

Ackley SF, Zimmerman SC, Brenowitz WD, Tchetgen Tchetgen EJ, Gold AL, Manly JJ, Mayeda ER, Filshtein TJ, Power MC, Elahi FM, Brickman AM, Glymour MM

Pathophysiologic mechanisms of cerebral endotheliopathy and stroke due to Sars-CoV-2.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Kakarla V, Kaneko N, Nour M, Khatibi K, Elahi F, Liebeskind DS, Hinman JD

MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SM

An introduction to therapeutic approaches to vascular cognitive impairment.

Cerebral Circulation - Cognition and Behavior

Hainsworth AH, Elahi FM, Corriveau RA

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

Evaluation of polygenic risk scores for 17 cancer types in relation to cognitive decline in the UK Biobank.

Alzheimer's & Dementia

Rebecca E Graff, Sarah F Ackley, Monica Ospina Romero, Scott C Zimmerman, Fanny M Elahi, Kun Ping Lu, John S Witte, M Maria Glymour

Fluid biomarkers of Alzheimer’s disease in the Systolic Blood Pressure Intervention Trial.

Alzheimer's & Dementia

Nicholas M Pajewski, Fanny M Elahi, Joachim H Ix, Ilya M Nasrallah, David M Reboussin, Manjula Kurella Tamura, Clinton B Wright, Jason Hinman, Lindsay M Miller, Tiffany L Sudduth, Donna M Wilcock, Jeff D Williamson

Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Kaitlin B. Casaletto, Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Fanny M. Elahi, Danielle Brushaber, Tatiana M. Foroud, Leah K. Forsberg, Anna M. Karydas, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer, ARTFL and LEFFTDS Consortium Investigators

ß-amyloid and tau drive early Alzheimer’s disease decline while glucose hypometabolism drives late decline.

Alzheimer's & Dementia

Tyler C Hammond, Xin Xing, David W, Kwangsik Nho, Paul K Crane, Fanny M Elahi, David Ziegler, Gongbo Liang, Qiang Cheng, Nathan Jacobs, Ai-Ling Lin, Alzheimer's Disease Neuroimaging Initiative

Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH

Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection.

Stroke

Kaneko N, Satta S, Komuro Y, Muthukrishnan SD, Kakarla V, Guo L, An J, Elahi F, Kornblum HI, Liebeskind DS, Hsiai T, Hinman JD

Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults.

Journal of the International Neuropsychological Society : JINS

Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer JH

Sex-related differences in the relationship between ß-amyloid and cognitive trajectories in older adults.

Neuropsychology

Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH

Editorial: Lipids in the Brain.

Frontiers in neurology

Albi E, Alessenko AV, Elahi FM, Ledesma MD

Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH

REM sleep is associated with white matter integrity in cognitively healthy, older adults.

PloS one

Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM

ß-amyloid and tau drive early Alzheimer's disease decline while glucose hypometabolism drives late decline.

Communications biology

Hammond TC, Xing X, Wang C, Ma D, Nho K, Crane PK, Elahi F, Ziegler DA, Liang G, Cheng Q, Yanckello LM, Jacobs N, Lin AL

Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB

Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning.

Brain, behavior, and immunity

Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH

Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Abner EL, Elahi FM, Jicha GA, Mustapic M, Al-Janabi O, Kramer JH, Kapogiannis D, Goetzl EJ

The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases.

Expert review of molecular diagnostics

Baldacci F, Mazzucchi S, Della Vecchia A, Giampietri L, Giannini N, Koronyo-Hamaoui M, Ceravolo R, Siciliano G, Bonuccelli U, Elahi FM, Vergallo A, Lista S, Giorgi FS, Hampel H

An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury.

PloS one

Altendahl M, Maillard P, Harvey D, Cotter D, Walters S, Wolf A, Singh B, Kakarla V, Azizkhanian I, Sheth SA, Xiao G, Fox E, You M, Leng M, Elashoff D, Kramer JH, Decarli C, Elahi F, Hinman JD

Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.

Nature

Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

Acute Insulin Resistance and Rapid Alterations in Neuronal Derived Blood Exosome Concentration After Branched Endovascular Aortic Aneurysm Repair.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Hiramoto JS, Elahi FM, Gasper WJ, Reilly LM, Chuter TA, Goetzl EJ

Concise Review: Preclinical Translation of Exosomes Derived from Mesenchymal Stem/Stromal Cells.

Stem cells (Dayton, Ohio)

Elahi FM, Farwell DG, Nolta JA, Anderson JD

Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Filshtein TJ, Brenowitz WD, Mayeda ER, Hohman TJ, Walter S, Jones RN, Elahi FM, Glymour MM

STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS.

Alzheimer's & Dementia

Sophia A. Weiner-Light, Samantha Walters, Nina Djukic, Michelle You, Devyn Cotter, Marie Altendahl, Fanny Elahi, Adam M. Staffaroni, Cutter A. Lindbergh, Joel H. Kramer, Kaitlin B. Casaletto

Neuron-Derived Exosome Proteins May Contribute to Progression From Repetitive Mild Traumatic Brain Injuries to Chronic Traumatic Encephalopathy.

Frontiers in neuroscience

Goetzl EJ, Ledreux A, Granholm AC, Elahi FM, Goetzl L, Hiramoto J, Kapogiannis D

A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.

Human brain mapping

Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH

Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time.

Frontiers in aging neuroscience

Bettcher BM, Neuhaus J, Wynn MJ, Elahi FM, Casaletto KB, Saloner R, Fitch R, Karydas A, Kramer JH

Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.

Brain : a journal of neurology

Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ

Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults.

Neurobiology of aging

Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH

Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia.

Alzheimer's & dementia (Amsterdam, Netherlands)

Winston CN, Goetzl EJ, Schwartz JB, Elahi FM, Rissman RA

Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Goetzl EJ, Elahi FM, Mustapic M, Kapogiannis D, Pryhoda M, Gilmore A, Gorgens KA, Davidson B, Granholm AC, Ledreux A

"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.

Frontiers in aging neuroscience

Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.

Acta neuropathologica

Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS

New Antibody-Free Mass Spectrometry-Based Quantification Reveals That C9ORF72 Long Protein Isoform Is Reduced in the Frontal Cortex of Hexanucleotide-Repeat Expansion Carriers.

Frontiers in neuroscience

Viodé A, Fournier C, Camuzat A, Fenaille F, Latouche M, Elahi F, Ber IL, Junot C, Lamari F, Anquetil V, Becher F

ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE.

Alzheimer's & Dementia

Fanny Elahi, Marie Altendahl, Teresa J. Filshtein, Kaitlin Casaletto, Adam M. Staffaroni, Wilfredo Rivera Contreras, Anna M. Karydas, Yann Cobigo, Evan Fletcher, Baljeet Singh, Oliver Martinez, Howard J. Rosen, Jason Hinman, Katerina Akassoglou, Maria Glymour, Charlie S. DeCarli, Edward J. Goetzl, Joel H. Kramer

Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH

A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence?

Cytokine

Casaletto KB, Elahi FE, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher B, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH

Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.

Neurobiology of aging

Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH

The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH

Neuroimaging in Dementia.

Seminars in neurology

Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD

Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers.

Neurology

Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.

NeuroImage. Clinical

Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ

A clinicopathological approach to the diagnosis of dementia.

Nature reviews. Neurology

Elahi FM, Miller BL

The concept of FDG-PET endophenotype in Alzheimer's disease.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

During EH, Osorio RS, Elahi FM, Mosconi L, de Leon MJ

A critical review of dissociative trance and possession disorders: etiological, diagnostic, therapeutic, and nosological issues.

Canadian journal of psychiatry. Revue canadienne de psychiatrie

During EH, Elahi FM, Taieb O, Moro MR, Baubet T

Functional genetic analysis of mutations implicated in a human speech and language disorder.

Human molecular genetics

Vernes SC, Nicod J, Elahi FM, Coventry JA, Kenny N, Coupe AM, Bird LE, Davies KE, Fisher SE