Alzheimer's & Dementia

Sleep patterns differ across Alzheimer’s disease phenotypes: Implications for selective vulnerability and customized treatment.

Neus Falgàs Martínez, Leslie Ruoff, Youssef M Essanaa, Michael M Le, Michelle You, Joel H Kramer, Keith A Vossel, Thomas Neylan, Christine M Walsh, Kamalini G Ranasinghe, Lea T. Grinberg

Degeneration of human orexinergic neurons across Braak stages of Alzheimer’s disease: Implication for pathogenesis, sleep dysfunction, and therapy.

Alzheimer's & Dementia

Eva Larsen, Jun Yeop Oh, Mihovil Mladinov, Caroline Lew, Song Li, Thomas Neylan, William W. Seeley, Salvatore Spina, Christine M Walsh, Lea T. Grinberg

CSF and plasma placental growth factor as a biomarker for small-vessel damage in VCID.

Alzheimer's & Dementia

Tiffany L Sudduth, Zachary Winder, Fanny M Elahi, Peter T Nelson, Gregory A Jicha, Donna M Wilcock

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

Alzheimer's & Dementia

Ignacio Illán-Gala, Kaitlin B. Casaletto, Sergi Borrego-Écija, Eider M Arenaza-Urquijo, Amy Wolf, Yann Cobigo, Sheng-Yang Matthew Goh, Adam M. Staffaroni, Daniel Alcolea, Juan Fortea, Rafael Blesa, Jordi Clarimon, M. Florencia Iulita, Anna Brugulat-Serrat, Albert Lladó, Lea T. Grinberg, Kate L Possin, Katherine P Rankin, Joel H Kramer, Gil D. Rabinovici, Adam L. Boxer, William W. Seeley, Virginia Sturm, Maria Luisa Gorno Tempini, Bruce L. Miller, Raquel Sanchez-Valle, David C. Perry, Alberto Lleó, Howard J. Rosen

A phase 1b, randomized, double-blind, placebo-controlled, parallel cohort safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy study of intravenously infused BIIB092 in patients with four different primary tauopathy syndromes.

Alzheimer's & Dementia

Peter A. Ljubenkov, Lawren Vandevrede, Julio C. Rojas, Richard Tsai, Mary Koestler, Danielle Graham, Tien Dam, Adam L. Boxer

Objective home sleep profiles differentiate Alzheimer disease from a-synucleinopathies.

Alzheimer's & Dementia

Daniel J. Levendowski, Bradley F. Boeve, Thomas Neylan, Christine M. Walsh, Debby W. Tsuang, David H. Salat, Joanne M. Hamilton, Leslie Ruoff, Sarah Payne, David Shprecher, Joyce Lee-Iannotti, Philip R. Westbrook, Chris Berka, Gandis Mazeika, Erik K. St. Louis

Sleep patterns differ across Alzheimer’s disease phenotypes: Implications for selective vulnerability and customized treatment.

Degeneration of human orexinergic neurons across Braak stages of Alzheimer’s disease: Implication for pathogenesis, sleep dysfunction, and therapy.

CSF and plasma placental growth factor as a biomarker for small-vessel damage in VCID.

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

A phase 1b, randomized, double-blind, placebo-controlled, parallel cohort safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy study of intravenously infused BIIB092 in patients with four different primary tauopathy syndromes.

Objective home sleep profiles differentiate Alzheimer disease from a-synucleinopathies.

Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology.

The Lonafarnib target, Rhes, is uniquely dysregulated in tauopathies: A human postmortem study.

Structural basis for recognition of the Hsp90 closed, ATP state by the TPR-containing co-chaperone FKBP51.

Neuronal correlates of sleep in neurodegenerative diseases.

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Alzheimer's & Dementia

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